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A clinical trial of glutathione supplementation in autism spectrum disorders - PMC

In humans, circulating MOTS-c levels have been found to be lower in people with type 2 diabetes and inversely correlated with markers of insulin resistance like fasting insulin and HOMA-IR

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Both LIRA and SEMA have demonstrated nephroprotective effects in individuals with diabetes, suggesting that systolic blood pressure and HbA1c levels—rather than weight—are the most influential mediators, although other factors also play a role (Fig