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ASK1 goes on to bind to TRAF2, which in turn activates downstream-signaling cascades, including the MKK3/4/6–p38 and MKK4/7–JNK signaling pathways 36,37 (Figure 4)
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Participants showed significant reductions in waist circumference, systolic and diastolic blood pressure, glycated hemoglobin, fasting glucose, insulin levels, and lipid profiles
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