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The activation of the UPR begins by the dissociation of glucose-regulating proteins (GRPs) from three types of ER transmembrane anchors, namely inositol-requiring protein 1 (IRE1), activating transcription factor 6 (ATF6), or protein kinase RNA-like ER kinase (PERK) (6)
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Therefore, we chose not to include bilirubin in the analysis for this study
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