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This activation reduces the inhibitory binding between Caveolin-1 and eNOS, allowing greater eNOS activation and nitric oxide production—with laboratory studies showing BPC-157 at 1 μg/ml increases NO production 1.35-fold compared to controls
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[166] : 177 In parallel Annette Vogel was also using enzyme-linked immunosorbent assays (ELISA) to determine using a virus neutralisation test (VNT) if the candidates were inducing sufficient neutralising antibodies
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