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Conversely, progranulin and its derivative peptide atsttrin can bind to the TNF receptors to inhibit the phenotype and function associated with LPS-induced M1 macrophage polarization via the nuclear factor kappa-B (NF-κB) and MAPK signaling pathways [49]
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[DOI] [PubMed] [Google Scholar] 248.Levy EJ, Anderson ME, Meister A
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