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PDF) The Effect of the Human Plasma Molecule GHK-Cu on Stem Cell Actions and Expression of Relevant Genes

FIGURE 4 (B) The electrostatic profiles of both protein models, with 180° rotations shown on the right

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Thus, it appears necessary that low molecular weight hematopoietic substances that can possibly replace biologically active proteinaceous pharmaceuticals derived from the living body such as G-CSF need to have a property of exhibiting a hematopoiesis promoting effect by directly acting on bone marrow stem cells and/or precursor cells as well as a property of being capable of utilizing a mechanism that the pharmaceutical itself is administered in a form that enables efficient delivery to the bone marrow or the pharmaceutical efficiently reaches the bone marrow in the living body