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Interestingly in this study remifentanil (0.3β0.6 ΞΌg/kg per min) suppressed mainly proinflammatory cytokines such as IL-6, TNF, and IFN-Ξ³, but did not significantly affect the anti-inflammatory cytokine IL-10
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The use of natural substances, such as trehalose and glycerol, which have been demonstrated to be successful in maintaining cell viability and functionality, is one of the advances in cryoprotectant solutions [34,1,40]
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