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Consistent with this, a recent study in a maternal immune activation mouse model found that offspring exhibited hyperactivation of the PI3K/AKT/mTOR pathway alongside suppressed autophagic function and elevated NLRP3 inflammasome activity, and that pharmacological mTOR inhibition with rapamycin restored autophagic activity, reduced NLRP3-dependent neuroinflammation, and ameliorated schizophrenia-like behavioral abnormalities [84]
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Quanitity:90 x 500 mg
Cells were suspended in HBSS containing CaCl 2 and MgCl 2 (Invitrogen, Carlsbad, CA) supplemented with 0.5% BSA (Invitrogen) and 2% FBS (Hyclone, Logan, UT), and counted using a hemocytometer
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