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Organ transplant recipients on immunosuppressive therapy, adults with active autoimmune flares, pregnant or breastfeeding women (Zadaxin is Category C), adults under 18, and anyone with known hypersensitivity
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Further, the extraordinary affinity of HGF for Dihexa (Kd=2.2 x 10 "13 M) suggests that normally non- biologically active levels of HGF become physiologically relevant in the presence of a high affinity mimetic
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