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Recommendations for diagnosis and management of metformin-induced vitamin B12 (Cbl) deficiency - ScienceDirect
Moreover, ROS are involved in the TXNIP and GNPAT signaling pathways (Xu et al., 2020)
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This may be attributed to the role of metformin in reducing the production of sFlt-1 and soluble endoglin by endothelial cells, trophoblasts, and syncytiotrophoblasts, and modulating anti-angiogenic factors at the mitochondrial level (Romero et al., 2017)
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