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NU6300 improved the pathology of DSS-induced acute colitis, GSDMD cleavage, and inflammatory cytokine release
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ALA improved digital sensory nerve conduction velocity (NCV) but not sciatic-tibial, corrected endoneurial nutritive but not composite NBF, increased mitochondrial oxidative state without fixing nerve energy depletion, and enhanced polyol pathway intermediate accumulation without depleting myoinositol or taurine
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