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Notably, kidney-qi deficiency parallels immune dysfunction, blood stasis reflects microcirculatory disturbance, dampness–heat corresponds to metabolic and oxidative stress, and phlegm aligns with metabolic imbalance and impaired autophagy
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NLY01, a GLP-1R agonist, effectively blocks A1 astrocyte activation by inhibiting microglial release of IL-1α, TNFα, and C1q
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