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doi: 10.3390/v16121944 25 BhattDKBoermaABustosSOde GruijlTDvan den BosHHoebenRCet al

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Different reactive oxygen species (ROS) generators contribute to NAFLD inflammatory and fibrotic progression, which is quite strictly linked to the lipotoxic liver injury from fatty acids and/or a wide variety of their biologically active metabolites in the context of either a two-hit or a (more recent) multiple parallel hits theory

It is involved in various biochemical processes