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295 In addition, high expression of TLR4 can increase H 2 O 2 production in the colonic mucosa of UC mice, induce redox activity in the mucosa, exacerbate oxidative stress, and promote the disease progression of UC
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The differentially expressed genes were filtered using the condition “Fold change ≥2 or ≤−2” and the genes that fulfilled that condition were listed (Supplementary Data 1–3)
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