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Glutathione is the body's most powerful antioxidant and plays a primary role in the protection of all cells from daily metabolic stress, oxidative stress and toxic chemicals. Deficiency of glutathione contributes to

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Several stillbenes derivatives from natural and synthetic sources (Figure 8) have been investigated for their tyrosinase inhibition activity including: resveratrol from Morus alba 319 , Pleurotus ferulae 135 , vitis viniferae caulis 320 , Carignan grape juice 321 Artocarpus gomezianus 322 and Streptomyces avermitilis MA4680 323 and also, its derivatives fro m Dipterocarpaceae plants 324 and synthetic sources 325 , oxyresveratrol 326 from Morus australis 327 , Morus alba L (IC 50 = 0.10 ± 0.01 µM) 249 and Cudrania cochinchinensis (IC 50 = 2.33 µM) 255 , azo-resveratrol and its derivatives such as (E)-2-((2,4-dihydroxyphenyl)diazenyl) phenyl 4 methylbenzenesulfonate 328 and azo -oxyresveratrol 329 , trans -resveratrol from Streptomyces avermitilis MA4680 313 , a resveratrol dimer named gnetin C, from melinjo (Gnetum gnemon ) 330