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Concerning PD, oral features associated with the disease such as dysphagia, salivary pH and drooling may influence the oral microbiota by altering the β-diversity index and favoring the growth of opportunistic oral microbes and Lactobacillus species, which may exacerbate the clinical symptoms and correlate with worse Hamilton Anxiety Scale and Hamilton Depression Rating Scale scores [70,496,497]
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Truncation and substitution analyses were conducted on the initial 20 amino acids, resulting in the design of an octamer with high affinity for BNIP3 and BAX
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