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These knock in models highlight potential shortcomings of other TDP-43 models relying on overexpression to induce behavioural phenotypes in mice which may not reflect the underlying biology of TDP-43 in ALS/FTD
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International Journal of Clinical Medicine Vol.2 No.4(2011), Article ID:7567,9 pages DOI:10.4236/ijcm.2011.24084 Vasoactive Intestinal Peptide (VIP) and VIP Receptors—Elucidation of Structure and Function for Therapeutic Applications 1 Department of Medicine and Bioregulatory Science, Graduate School of Medical Science, Kyushu University, Fukuoka, Japan
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