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Glutathione is the master antioxidant, and the reason it matters is not the molecule itself but how you get it into the cell. It is the primary intracellular antioxidant, produced in the

In a phase II trial, 38% of relapsed SCLC patients with methylated O-6-methylguanine-DNA methyltransferase (MGMT) DNA-repair gene responded to temozolomide, compared to 7% with unmethylated MGMT, 89 suggesting MGMT methylation may have utility as a biomarker for temozolomide response, consistent with studies in glioblastoma

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