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Guidelines for the diagnosis and management of cystathionine beta-synthase deficiency - PMC
The related mechanisms further were confirmed related to the promotion of cell proliferation and minimization of DNA damage in splenocytes and bone marrow
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Aluminum can also enhance excitotoxicity by inducing apoptosis of astrocytes, which are thought to be a primary site of aluminum accumulation.[104] Indeed, research evidence shows that, apart from providing trophic support to neurons, astrocytes also play a crucial role in protecting neurons from excitotoxic damage by mediating the clearance of excess glutamate and its storage within the astrocyte.[1] When the astrocytes are dying, this glutamate is released into the extra-neuronal space and becomes excitotoxic
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