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Guidelines for preventing health-care-associated pneumonia: recommendations of CDC and the Healthcare Infection Control Practices Advisory Committee
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Despite its physiological importance, amylin has historically been extremely difficult to study and use as a research compound: the native peptide is notoriously amyloidogenic, aggregating rapidly into β-sheet fibrils at physiological pH and forming the characteristic amyloid deposits found in pancreatic islets of patients with type-2 diabetes
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