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patient in intramuscular arm – provide appointments for injections · Visit 2 (week 8) Anamnesis: record lifestyle habits and use of alcohol Symptoms: if pathological at the first visit, record paresthesia, asthenia, loss or reduction of appetite, sadness or change in level of happiness, and concomitant pharmacological treatment Physical examination: if pathological at the first visit examine for Hunter’s glositis, positional and vibrational sensitivity Record concomitant treatment Request analyses to be performed one week before next visit: haemogram and serum vitamin B12 Questionnaires: EuroQoL-5D Assessment of adverse effects Therapeutic plan: patient in oral arm – provision of medication

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Results Allicin improves post-stroke functional impairment, including behavior and cerebral infarct size Previous studies showed that allicin could reduce cerebral infarction areas, neuronal apoptosis, myeloperoxidase (MPO) activity, and tumor necrosis factor (TNF)‑α levels in serum to protect the brain from cerebral ischemia/reperfusion injury [7]