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Epithalon (also spelled Epitalon or Epithalone) is a synthetic tetrapeptide developed from research into pineal gland extracts, particularly a bovine pineal extract called epithalamin. It was largely pioneered by Russian gerontologist Vladimir
Similar in vitro work showed that HGF promoted dendritic arborization in hippocampal neurons, an effect that could be blocked by NMDA receptor antagonists and was dependent on intracellular calcium and CaMKII activity [2]
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