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In contrast, Group II and Group III mGluRs are generally found presynaptically and are coupled to Gi/o proteins, inhibiting adenylate cyclase activity and reducing cyclic AMP (cAMP) levels, which serves to inhibit neurotransmitter release and modulate synaptic strength
AHK-Cu peptide
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Chromatographic separation was performed using a Vanquish ultra high performance liquid chromatography (UHPLC) system with a column temperature of 40°C, a flow rate of 0.2 mL/min, and the mobile phase consisting of A: 0.1% formic acid and B: methanol
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