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A study in human volunteers demonstrated that DSIP administration normalized cortisol secretion patterns and reduced stress-related sleep disruption (Polleri et al., Psychopharmacology, 1985
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81 This treatment also ameliorates glomerular hyperfiltration, improves endothelial function and survival, reduces the production of reactive oxygen species, C-reactive protein and interleukin 6, increases vasodilator levels, and decreases the levels of vasoconstrictors
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