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Vitamin B2 (Riboflavin) Plays a role in cellular energy production and antioxidant pathways, supporting mitochondrial function and tissue repair

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This upregulation promotes mitochondrial biogenesis, reduces apoptotic signaling, and inhibits inflammatory cascade responses, highlighting a mechanism through which HBO attenuates inflammation[68], By modulating these conserved cascades—notably via SIRT1 activation and regulation of apoptosis—HBO therapy contributes to improved functional recovery following central nervous system injuries, suggesting its potential to mitigate post-cardiac arrest encephalopathy by targeting shared inflammatory and apoptotic pathways in global cerebral ischemia[69, 70]