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Platelet-Rich Plasma (PRP) Platelet-rich plasma therapy for lumbar disc degeneration works through its bioactive constituents, particularly growth factors including platelet-derived growth factor (PDGF), transforming growth factor-beta (TGF-β), and vascular endothelial growth factor (VEGF), which facilitate cellular proliferation, extracellular matrix restoration, and tissue repair

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These heterodimeric assemblies produce multiple receptor subtypes commonly referred to as AMY1, AMY2, and AMY3 receptors

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