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Although all identified CerS enzymes exhibit similar Km values (affinity for substrates), they vary in their selectivity for acyl-CoAs depending on the length of the acyl chain ( The role of ceramides in the brain is essential for maintaining the structure and function of cell membranes, contributing to their integrity, fluidity and stability (Mencarelli and Martinez-Martinez, 2013)
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A similar study by Kern et al
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