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Regulation of active site coupling in glutamine-dependent NAD+ synthetase | Nature Structural & Molecular Biology

Histologically, iron is initially deposited in the zone 3 Kupffer cells and it gradually extends to the entire lobe

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Very early, it was seen that transplatin is not active when tested in animal models, and therefore it was postulated that the cis geometry is crucial for the cytotoxic activity for which two reasons where identified (Figure 7.27)