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More specifically, the prominent role of Nrf2 pathway in oxidative stress handling throughout life is further emphasized by the fact that the inhibition of this pathway by progerin has been incriminated in the premature aging occurring during progeria disease (Silva-Palacios et al., 2016)
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Vitamin B12 may increase the chance of an artery narrowing around a stent (a device that widens a blocked artery) and it could potentially harm the optic nerves, causing blindness in people with the rare hereditary condition called Leber's disease
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