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Nutrition, GH/IGF-1 signaling, and cancer - ScienceDirect
When excess ROS overwhelms the antioxidant systems, oxidative stress occurs, leading to harmful effects on cellular organisms, such as inducing DNA mutations (28, 31, 33), altering lipid metabolism (31, 34), and further inducing cell death (5)
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To encourage uptake by BMECs and prevent nucleic acids from enzymatic destruction, carriers are often necessary for the delivery of therapeutic nucleic acids
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